Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.52 |
| ▸ | HTT | P42858 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20231932 | 1.00 | MAPT (0.52) | MAPTALDH1A1HTTLMNAMAPK1 | |
| SCHEMBL20231922 | 0.89 | MAPT (0.50) | MAPTALDH1A1HTTLMNAMAPK1 | |
| SCHEMBL710108 | 0.87 | ALDH1A1 (0.51) | MAPTALDH1A1HTTLMNAMAPK1 | |
| SCHEMBL20521398 | 0.84 | SMN1; SMN2 (0.49) | MAPTALDH1A1HTTLMNAMAPK1 | |
| SCHEMBL30221908 | 0.84 | SMN1; SMN2 (0.49) | MAPTALDH1A1HTTLMNAMAPK1 | |
| SCHEMBL23703376 | 0.81 | SUV39H2 (0.47) | MAPTALDH1A1HTTLMNAMAPK1 | |
| SCHEMBL19063936 | 0.81 | MAPT (0.63) | MAPTALDH1A1LMNASMN1; SMN2GAA | |
| SCHEMBL21937028 | 0.81 | MAPT (0.51) | MAPTALDH1A1HTTLMNAMAPK1 | |
| SCHEMBL20046702 | 0.80 | LMNA (0.52) | MAPTALDH1A1HTTLMNASMN1; SMN2 | |
| SCHEMBL8257373 | 0.79 | ALDH1A1 (0.60) | MAPTALDH1A1HTTLMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4630414-A1 | TARGETED PROTEIN DEGRADATION USING BIFUNCTIONAL COMPOUNDS THAT BIND UBIQUITIN LIGASE AND TARGET MCL-1 PROTEIN | Captor Therapeutics S.A. (PL) | 2025-10-15 | — | — | EP | disclosed |
| WO-2024121256-A1 | TARGETED PROTEIN DEGRADATION USING BIFUNCTIONAL COMPOUNDS THAT BIND UBIQUITIN LIGASE AND TARGET MCL-1 PROTEIN | CAPTOR THERAPEUTICS S.A. (PL) | 2024-06-13 | — | — | WO | disclosed |