Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 11/20 | 0.47 |
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | FNTA | P49354 | 1/20 | 0.39 |
| ▸ | FNTB | P49356 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1982664 | 1.00 | AR (0.47) | ARDHFRFFAR1POLBLMNA | |
| SCHEMBL22026242 | 0.80 | AR (0.47) | ARLMNATSHRALDH1A1GAA | |
| SCHEMBL1191959 | 0.79 | AR (0.55) | ARLMNATSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL5993012 | 0.78 | MGLL (0.57) | DHFRFFAR1POLBLMNAALDH1A1 | |
| SCHEMBL9900459 | 0.78 | AR (0.43) | ARPOLBLMNATSHRALDH1A1 | |
| SCHEMBL9905740 | 0.77 | AR (0.42) | ARPOLBALDH1A1 | |
| SCHEMBL1978201 | 0.75 | SMN1; SMN2 (0.51) | ARLMNATSHRALDH1A1MEN1 | |
| SCHEMBL30939585 | 0.75 | SMN1; SMN2 (0.51) | ARLMNATSHRALDH1A1MEN1 | |
| SCHEMBL1773418 | 0.75 | AR (0.54) | ARLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL21953180 | 0.75 | AR (0.46) | ARPOLBLMNATSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118267386-A | Modulators of KV3 channels for the treatment of pain | 奥提芙尼治疗学有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-108472288-B | Modulators of KV3 channels for the treatment of pain | 奥提芙尼治疗学有限公司 | 2024-05-28 | — | — | CN | disclosed |