Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 14/20 | 0.57 |
| ▸ | DHFR | P00374 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CCR6 | P51684 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | FNTA | P49354 | 1/20 | 0.43 |
| ▸ | FNTB | P49356 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31180015 | 0.92 | MGLL (0.62) | MGLLFAAHALDH1A1HSP90AA1HPGD | |
| SCHEMBL31179978 | 0.85 | MGLL (0.61) | MGLLFAAHALDH1A1HSP90AA1HPGD | |
| SCHEMBL31179944 | 0.82 | MGLL (0.76) | MGLLFAAHALDH1A1HSP90AA1HPGD | |
| SCHEMBL25398729 | 0.82 | MGLL (0.76) | MGLLFAAHALDH1A1HSP90AA1HPGD | |
| SCHEMBL31174389 | 0.81 | MGLL (0.64) | MGLLFAAHALDH1A1HSP90AA1HPGD | |
| SCHEMBL24576257 | 0.80 | DHFR (0.62) | DHFRALDH1A1HPGDHTTMEN1 | |
| SCHEMBL31179932 | 0.79 | MGLL (0.57) | MGLLFAAHALDH1A1HSP90AA1HPGD | |
| SCHEMBL31180017 | 0.78 | MGLL (0.63) | MGLLFAAHALDH1A1HSP90AA1HTT | |
| SCHEMBL1982664 | 0.78 | AR (0.47) | DHFRALDH1A1HTTMEN1LMNA | |
| SCHEMBL30939596 | 0.78 | AR (0.47) | DHFRALDH1A1HTTMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012065139-A2 | ENTPD5 INHIBITORS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2012-05-18 | — | — | WO | disclosed |