Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | TGM2 | P21980 | 2/20 | 0.43 |
| ▸ | PNMT | P11086 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 2/20 | 0.41 |
| ▸ | TLR2 | O60603 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9654834 | 0.95 | SIRT2 (0.48) | SIRT2SIRT1CTSKTGM2ACE | |
| SCHEMBL23327018 | 0.95 | SIRT2 (0.48) | SIRT2SIRT1CTSKTGM2ACE | |
| SCHEMBL9654831 | 0.95 | SIRT2 (0.48) | SIRT2SIRT1CTSKTGM2ACE | |
| SCHEMBL30146700 | 0.92 | PNMT (0.42) | SIRT2SIRT1CTSKTGM2PNMT | |
| SCHEMBL2551608 | 0.91 | FOLH1 (0.45) | TGM2PNMTACE | |
| SCHEMBL2551604 | 0.91 | FOLH1 (0.45) | TGM2PNMTACE | |
| SCHEMBL28030109 | 0.91 | TLR2 (0.45) | SIRT2SIRT1TGM2PNMTACE | |
| SCHEMBL9385177 | 0.90 | FNTA (0.46) | CTSKTGM2CTSL | |
| SCHEMBL22804121 | 0.90 | FNTA (0.46) | CTSKTGM2CTSL | |
| SCHEMBL27911668 | 0.90 | TGM2 (0.40) | SIRT2SIRT1TGM2PNMTACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118359676-A | Modified peptides as Trem-1 inhibitors | 武汉人福创新药物研发中心有限公司 | 2024-07-19 | — | — | CN | disclosed |