Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | AHR | P35869 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | PLK1 | P53350 | 1/20 | 0.33 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.33 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.33 |
| ▸ | PLK2 | Q9NYY3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21002217 | 1.00 | GRM5 (0.44) | GRM5L3MBTL1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL30940512 | 0.81 | TYK2 (0.41) | L3MBTL1MAPTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL28408759 | 0.80 | GRM5 (0.44) | GRM5L3MBTL1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL30940527 | 0.80 | GRM5 (0.44) | GRM5L3MBTL1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL21001870 | 0.77 | L3MBTL1 (0.44) | GRM5L3MBTL1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL30940530 | 0.73 | TYK2 (0.39) | MAPTRAB9ASMN1; SMN2NPC1AHR | |
| SCHEMBL21002298 | 0.73 | GRM5 (0.42) | GRM5L3MBTL1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL30940504 | 0.73 | GRM5 (0.42) | GRM5L3MBTL1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL20985324 | 0.72 | SYK (0.51) | GRM5L3MBTL1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL30940484 | 0.72 | SYK (0.51) | GRM5L3MBTL1MAPTRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111315737-B | Heteroaryl compounds substituted with sulfone pyridinylalkylamides | 百时美施贵宝公司 | 2024-06-18 | — | — | CN | disclosed |