Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TKT | P29401 | 1/20 | 0.33 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.31 |
| ▸ | KCNK13 | Q9HB14 | 1/20 | 0.30 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4278544 | 0.80 | TDP1 (0.39) | NOTUM | |
| SCHEMBL16478722 | 0.75 | CYP2A6 (0.35) | EGLN2KCNK13 | |
| SCHEMBL16832891 | 0.75 | EGLN2 (0.33) | EGLN2KCNK13 | |
| SCHEMBL3294798 | 0.75 | EGLN2 (0.41) | EGLN2SOS2NOTUM | |
| SCHEMBL30942638 | 0.71 | EGLN2 (0.30) | EGLN2KCNK13 | |
| SCHEMBL21199960 | 0.71 | HSD11B1 (0.44) | TKTHSD11B1SOS2 | |
| SCHEMBL27826103 | 0.70 | TDP1 (0.32) | — | |
| SCHEMBL24536032 | 0.67 | MEN1 (0.53) | — | |
| SCHEMBL24536033 | 0.67 | PANK3 (0.33) | HSD11B1 | |
| SCHEMBL21639440 | 0.67 | CYP1A2 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024134541-A1 | HETEROCYCLIC COMPOUNDS AS ENT INHIBITORS AND COMPOUNDS FOR USE IN THE TREATMENT OF CANCERS | iTeos Belgium SA (BE) | 2024-06-27 | — | — | WO | disclosed |