Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | DHFR | P00374 | 3/20 | 0.40 |
| ▸ | ELANE | P08246 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31306898 | 0.84 | ALDH1A1 (0.51) | ALDH1A1TSHRDHFRELANEMEN1 | |
| Hydrochloric Acid SCHEMBL10567076 | 0.76 | CHRM2 (0.46) | ALDH1A1MEN1KMT2AGAAPOLB | |
| SCHEMBL1929687 | 0.74 | ALOX12 (0.54) | ALDH1A1TSHRMEN1KMT2AMAPT | |
| SCHEMBL20997478 | 0.74 | ALOX12 (0.54) | ALDH1A1TSHRMEN1KMT2AMAPT | |
| SCHEMBL10567177 | 0.74 | SIGMAR1 (0.47) | ALDH1A1TSHRMEN1KMT2ACYP1A2 | |
| Hydrochloric Acid SCHEMBL6606867 | 0.73 | ALOX12 (0.53) | ALDH1A1TSHRMEN1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL10565198 | 0.73 | SIGMAR1 (0.48) | ALDH1A1TSHRMEN1KMT2ACYP1A2 | |
| SCHEMBL2257976 | 0.72 | ELANE (0.61) | ELANEMEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL20983872 | 0.71 | ALDH1A1 (0.54) | ALDH1A1TSHRDHFRELANEMEN1 | |
| SCHEMBL9242285 | 0.71 | ALDH1A1 (0.54) | ALDH1A1TSHRDHFRELANEMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4608810-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF USE TO TREAT HYPOPARATHYROIDISM AND OSTEOPOROSIS | Septerna, Inc. (US) | 2025-09-03 | — | — | EP | disclosed |
| WO-2024091498-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF USE TO TREAT HYPOPARATHYROIDISM AND OSTEOPOROSIS | SEPTERNA, INC. (US) | 2024-05-02 | — | — | WO | disclosed |