Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.40 |
| ▸ | FBP1 | P09467 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.39 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.39 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30944413 | 0.92 | FFAR2 (0.47) | P2RX7ALOX15GAAHTTNPC1 | |
| SCHEMBL30944418 | 0.88 | GAA (0.43) | P2RX7ALOX15GAAHTTNPC1 | |
| SCHEMBL31236385 | 0.87 | P2RX7 (0.48) | P2RX7ALOX15GAAHTTNPC1 | |
| SCHEMBL30944358 | 0.86 | NPC1 (0.42) | P2RX7ALOX15GAAHTTNPC1 | |
| SCHEMBL28525120 | 0.85 | ALOX15 (0.41) | P2RX7ALOX15GAAHTTNPC1 | |
| SCHEMBL30944317 | 0.85 | NPC1 (0.47) | P2RX7ALOX15GAAHTTNPC1 | |
| SCHEMBL30944396 | 0.83 | ALOX15 (0.47) | P2RX7ALOX15GAAHTTNPC1 | |
| SCHEMBL30944379 | 0.81 | P2RX7 (0.47) | P2RX7ALOX15GAAHTTNPC1 | |
| SCHEMBL30944383 | 0.77 | DYRK1A (0.56) | NPC1KMT2APOLBRAB9A | |
| SCHEMBL30944369 | 0.76 | GAA (0.44) | P2RX7ALOX15GAAHTTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118772080-A | Antimycobacterial heterocyclic amides | 克莱斯通公司 | 2024-10-15 | — | — | CN | claimed |
| CN-118772080-A | Antimycobacterial heterocyclic amides | 克莱斯通公司 | 2024-10-15 | — | — | CN | disclosed |
| CN-112423746-B | Novel antimycobacterial heterocyclic amides | 克莱斯通公司 | 2024-06-28 | — | — | CN | disclosed |