Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 7/20 | 0.76 |
| ▸ | SENP8 | Q96LD8 | 7/20 | 0.76 |
| ▸ | SENP7 | Q9BQF6 | 7/20 | 0.76 |
| ▸ | SENP6 | Q9GZR1 | 7/20 | 0.76 |
| ▸ | NPC1 | O15118 | 6/20 | 0.62 |
| ▸ | RAB9A | P51151 | 6/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | CLK1 | P49759 | 1/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.58 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.58 |
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | CNR2 | P34972 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30944371 | 0.86 | CYP2C19 (0.61) | CASP3SENP8SENP7SENP6NPC1 | |
| SCHEMBL28529433 | 0.85 | CASP3 (0.88) | CASP3SENP8SENP7SENP6NPC1 | |
| SCHEMBL30944295 | 0.85 | CASP3 (0.88) | CASP3SENP8SENP7SENP6NPC1 | |
| SCHEMBL30944345 | 0.84 | CASP3 (0.72) | CASP3SENP8SENP7SENP6NPC1 | |
| SCHEMBL28520783 | 0.81 | MAOA (0.51) | CASP3SENP8SENP7SENP6NPC1 | |
| SCHEMBL30944381 | 0.81 | MAOA (0.51) | CASP3SENP8SENP7SENP6NPC1 | |
| SCHEMBL30944304 | 0.81 | CASP3 (0.68) | CASP3SENP8SENP7SENP6NPC1 | |
| SCHEMBL28527459 | 0.81 | CASP3 (0.67) | CASP3SENP8SENP7SENP6NPC1 | |
| SCHEMBL30944332 | 0.81 | CASP3 (0.67) | CASP3SENP8SENP7SENP6NPC1 | |
| SCHEMBL30944378 | 0.81 | MAPT (0.64) | CASP3SENP8SENP7SENP6NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118772080-A | Antimycobacterial heterocyclic amides | 克莱斯通公司 | 2024-10-15 | — | — | CN | claimed |
| CN-118772080-A | Antimycobacterial heterocyclic amides | 克莱斯通公司 | 2024-10-15 | — | — | CN | disclosed |
| CN-112423746-B | Novel antimycobacterial heterocyclic amides | 克莱斯通公司 | 2024-06-28 | — | — | CN | disclosed |