Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.88 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.88 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.88 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.88 |
| ▸ | MAOA | P21397 | 1/20 | 0.75 |
| ▸ | MAOB | P27338 | 1/20 | 0.75 |
| ▸ | NPC1 | O15118 | 8/20 | 0.73 |
| ▸ | RAB9A | P51151 | 7/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.73 |
| ▸ | MEN1 | O00255 | 2/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.73 |
| ▸ | GFER | P55789 | 1/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | CLK1 | P49759 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.64 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30944295 | 1.00 | CASP3 (0.88) | CASP3SENP8SENP7SENP6MAOA | |
| SCHEMBL30944345 | 0.86 | CASP3 (0.72) | CASP3SENP8SENP7SENP6MAOA | |
| SCHEMBL30944347 | 0.85 | CASP3 (0.76) | CASP3SENP8SENP7SENP6MAOA | |
| SCHEMBL1621733 | 0.85 | MAOA (0.75) | CASP3SENP8SENP7SENP6MAOA | |
| SCHEMBL30944304 | 0.83 | CASP3 (0.68) | CASP3SENP8SENP7SENP6MAOA | |
| SCHEMBL13257159 | 0.82 | CASP3 (0.67) | CASP3SENP8SENP7SENP6MAOA | |
| SCHEMBL4909101 | 0.81 | NPC1 (0.70) | CASP3SENP8SENP7SENP6MAOA | |
| SCHEMBL30886547 | 0.81 | NPC1 (0.71) | CASP3SENP8SENP7SENP6MAOA | |
| SCHEMBL30944403 | 0.80 | MAOA (0.67) | CASP3SENP8SENP7SENP6MAOA | |
| SCHEMBL28530651 | 0.80 | MAOA (0.67) | CASP3SENP8SENP7SENP6MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112423746-A | Novel anti-mycobacterial heterocyclic amides | 克莱斯通公司 | 2021-02-26 | — | — | CN | claimed |
| CN-112423746-A | Novel anti-mycobacterial heterocyclic amides | 克莱斯通公司 | 2021-02-26 | — | — | CN | disclosed |