Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 7/20 | 0.55 |
| ▸ | NPC1 | O15118 | 7/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30944368 | 0.86 | RAB9A (0.76) | MAPTLMNARAB9ANPC1KMT2A | |
| SCHEMBL30944397 | 0.85 | RAB9A (0.63) | MAPTLMNARAB9ANPC1KMT2A | |
| SCHEMBL28535148 | 0.85 | RAB9A (0.63) | MAPTLMNARAB9ANPC1KMT2A | |
| SCHEMBL30944380 | 0.85 | RAB9A (0.63) | MAPTLMNARAB9ANPC1KMT2A | |
| SCHEMBL28529049 | 0.85 | RAB9A (0.63) | MAPTLMNARAB9ANPC1KMT2A | |
| SCHEMBL28527380 | 0.81 | MAPT (0.57) | MAPTLMNARAB9ANPC1KMT2A | |
| SCHEMBL30944402 | 0.81 | MAPT (0.57) | MAPTLMNARAB9ANPC1KMT2A | |
| SCHEMBL30944316 | 0.78 | LMNA (0.70) | MAPTLMNARAB9ANPC1KMT2A | |
| SCHEMBL28519838 | 0.73 | RAB9A (0.48) | MAPTLMNARAB9ANPC1KMT2A | |
| SCHEMBL30944371 | 0.72 | CYP2C19 (0.61) | MAPTLMNARAB9ANPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118772080-A | Antimycobacterial heterocyclic amides | 克莱斯通公司 | 2024-10-15 | — | — | CN | claimed |
| CN-118772080-A | Antimycobacterial heterocyclic amides | 克莱斯通公司 | 2024-10-15 | — | — | CN | disclosed |
| CN-112423746-B | Novel antimycobacterial heterocyclic amides | 克莱斯通公司 | 2024-06-28 | — | — | CN | disclosed |