Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 12/20 | 0.38 |
| ▸ | AKT1 | P31749 | 2/20 | 0.38 |
| ▸ | AKT2 | P31751 | 2/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30944799 | 0.85 | AKT1 (0.42) | AKT1AKT2 | |
| SCHEMBL30944802 | 0.85 | AKT1 (0.42) | AKT1AKT2 | |
| SCHEMBL24479249 | 0.73 | RAB9A (0.43) | AKT1AKT2NR1H4RAB9ANPC1 | |
| SCHEMBL30944809 | 0.73 | AKT1 (0.49) | AKT1AKT2 | |
| SCHEMBL4864402 | 0.72 | TGFBR1 (0.58) | TGFBR1MAPK14RAB9ANPC1 | |
| SCHEMBL24479429 | 0.71 | RAB9A (0.46) | TGFBR1AKT1AKT2NR1H4RAB9A | |
| SCHEMBL4859626 | 0.71 | TGFBR1 (0.59) | TGFBR1MAPK14RAB9ANPC1 | |
| SCHEMBL4878226 | 0.70 | TGFBR1 (0.59) | TGFBR1MAPK14 | |
| SCHEMBL24479345 | 0.70 | AKT1 (0.45) | AKT1AKT2RAB9ANPC1 | |
| SCHEMBL24479394 | 0.70 | AKT1 (0.45) | AKT1AKT2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4626896-A1 | POLYELECTROPHILIC METALATED HETEROCYCLES DERIVED FROM 2-(PYRIDIN-2-YL)IMIDAZO[1,2-A]PYRIDINE AND USE THEREOF AS CHEMOTHERAPEUTIC AGENTS | Universidad del País Vasco/Euskal Herriko Unibertsitatea (ES) | 2025-10-08 | — | — | EP | disclosed |
| WO-2024115550-A1 | POLYELECTROPHILIC METALATED HETEROCYCLES DERIVED FROM 2-(PYRIDIN-2-YL)IMIDAZO[1,2-A]PYRIDINE AND USE THEREOF AS CHEMOTHERAPEUTIC AGENTS | UNIVERSIDAD DEL PAÍS VASCO/EUSKAL HERRIKO UNIBERTSITATEA (ES) | 2024-06-06 | — | — | WO | disclosed |