Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 3/20 | 0.42 |
| ▸ | AKT2 | P31751 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 5/20 | 0.39 |
| ▸ | HTT | P42858 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30944799 | 1.00 | AKT1 (0.42) | AKT1AKT2SMN1; SMN2NPSR1MAPT | |
| SCHEMBL30944809 | 0.89 | AKT1 (0.49) | AKT1AKT2SMN1; SMN2NPSR1MAPT | |
| SCHEMBL30944792 | 0.85 | TGFBR1 (0.38) | AKT1AKT2 | |
| SCHEMBL30944790 | 0.83 | GAA (0.40) | AKT1AKT2SMN1; SMN2NPSR1MAPT | |
| SCHEMBL30944793 | 0.81 | HTR2C (0.42) | AKT1AKT2SMN1; SMN2NPSR1MAPT | |
| SCHEMBL25767845 | 0.78 | PTGS2 (0.49) | AKT1AKT2SMN1; SMN2NPSR1MAPT | |
| SCHEMBL30944798 | 0.77 | AKT1 (0.56) | AKT1AKT2SMN1; SMN2NPSR1MAPT | |
| SCHEMBL30944808 | 0.76 | AKT1 (0.52) | AKT1AKT2SMN1; SMN2NPSR1MAPT | |
| SCHEMBL25767821 | 0.74 | PTGS2 (0.43) | AKT1AKT2SMN1; SMN2NPSR1MAPT | |
| SCHEMBL25768293 | 0.72 | SMN1; SMN2 (0.38) | AKT1AKT2SMN1; SMN2NPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4626896-A1 | POLYELECTROPHILIC METALATED HETEROCYCLES DERIVED FROM 2-(PYRIDIN-2-YL)IMIDAZO[1,2-A]PYRIDINE AND USE THEREOF AS CHEMOTHERAPEUTIC AGENTS | Universidad del País Vasco/Euskal Herriko Unibertsitatea (ES) | 2025-10-08 | — | — | EP | disclosed |
| WO-2024115550-A1 | POLYELECTROPHILIC METALATED HETEROCYCLES DERIVED FROM 2-(PYRIDIN-2-YL)IMIDAZO[1,2-A]PYRIDINE AND USE THEREOF AS CHEMOTHERAPEUTIC AGENTS | UNIVERSIDAD DEL PAÍS VASCO/EUSKAL HERRIKO UNIBERTSITATEA (ES) | 2024-06-06 | — | — | WO | disclosed |