SCHEMBL30944906

SCHEMBL30944906

CCOC(=O)c1cn(C2CC2)c2c(OC)c(N)c(F)cc2c1=O

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 1/20 0.56
KCNH2 Q12809 5/20 0.53
GSK3B P49841 2/20 0.50
KDM4E B2RXH2 4/20 0.49
ALDH1A1 P00352 3/20 0.49
HPGD P15428 3/20 0.49
HSD17B10 Q99714 2/20 0.49
POLB P06746 1/20 0.49
PRKD3 O94806 1/20 0.49
ALOX15 P16050 1/20 0.49
OPRM1 P35372 1/20 0.49
CLK2 P49760 1/20 0.49
CLK4 Q9HAZ1 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
LMNA P02545 1/20 0.45
STAT3 P40763 1/20 0.44
TOP2A P11388 1/20 0.44
TOP2B Q02880 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27442162 1.00 ADRB2 (0.56) ADRB2KCNH2GSK3BKDM4EALDH1A1
SCHEMBL3134035 0.91 ADRB2 (0.61) ADRB2KCNH2KDM4EALDH1A1HPGD
SCHEMBL29391687 0.90 ADRB2 (0.61) ADRB2KCNH2GSK3BKDM4EALDH1A1
SCHEMBL1989474 0.90 ADRB2 (0.61) ADRB2KCNH2GSK3BKDM4EALDH1A1
SCHEMBL9693055 0.90 ADRB2 (0.65) ADRB2KCNH2ALDH1A1POLBOPRM1
SCHEMBL30891261 0.88 ADRB2 (0.56) ADRB2KCNH2GSK3BKDM4EALDH1A1
SCHEMBL30944930 0.88 ADRB2 (0.56) ADRB2KCNH2GSK3BKDM4EALDH1A1
SCHEMBL5704361 0.88 ADRB2 (0.56) ADRB2KCNH2GSK3BKDM4EALDH1A1
SCHEMBL7011678 0.88 ADRB2 (0.56) ADRB2KCNH2GSK3BKDM4EALDH1A1
SCHEMBL28386544 0.86 KCNH2 (0.65) KCNH2GSK3BKDM4EALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4644376-A1 NEW PHENYLQUINOLONE COMPOUND HAVING ANTIBACTERIAL AND ANTI-CANCER FUNCTIONS AND PREPARATION THEREOF Alphamol Science Ltd (Shanghai) (CN) 2025-11-05 EP disclosed
EP-4644391-A1 NOVEL PHENYLQUINOLONE COMPOUND HAVING ANTIBACTERIAL AND ANTICANCER FUNCTIONS, AND PREPARATION THEREOF Alphamol Science Ltd (Shanghai) (CN) 2025-11-05 EP disclosed
CN-118255716-A Novel phenyl quinolone compound with antibacterial and anticancer functions and preparation thereof 深圳阿尔法分子科技有限责任公司 2024-06-28 CN disclosed