Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.65 |
| ▸ | TOP2A | P11388 | 7/20 | 0.52 |
| ▸ | TOP2B | Q02880 | 7/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.49 |
| ▸ | STAT3 | P40763 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3134035 | 0.94 | ADRB2 (0.61) | ADRB2TOP2ATOP2BKCNH2STAT3 | |
| SCHEMBL29492858 | 0.92 | ADRB2 (0.68) | ADRB2TOP2ATOP2BKCNH2STAT3 | |
| SCHEMBL2844967 | 0.92 | ADRB2 (0.68) | ADRB2TOP2ATOP2BKCNH2STAT3 | |
| SCHEMBL10627001 | 0.90 | ADRB2 (0.66) | ADRB2TOP2ATOP2BKCNH2STAT3 | |
| SCHEMBL27442162 | 0.90 | ADRB2 (0.56) | ADRB2TOP2ATOP2BKCNH2STAT3 | |
| SCHEMBL30944906 | 0.90 | ADRB2 (0.56) | ADRB2TOP2ATOP2BKCNH2STAT3 | |
| SCHEMBL25669900 | 0.89 | ADRB2 (0.58) | ADRB2TOP2ATOP2BKCNH2STAT3 | |
| SCHEMBL7599453 | 0.89 | ADRB2 (0.65) | ADRB2TOP2ATOP2BKCNH2STAT3 | |
| SCHEMBL5704396 | 0.88 | ADRB2 (0.64) | ADRB2TOP2ATOP2BKCNH2STAT3 | |
| SCHEMBL143605 | 0.88 | ADRB2 (0.64) | ADRB2TOP2ATOP2BKCNH2STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5169853-A | Antibacterial agents; administering to mammals for infection | STERLING DRUG INC. (US) | 1992-12-08 | — | — | US | disclosed |
| US-5091384-A | ANTI-BACTERIAL QUINOLONE- AND NAPHTHYRIDONE-CARBOXYLIC ACID COMPOUNDS | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1992-02-25 | — | — | US | disclosed |
| US-5075319-A | Bactericides | STERLING DRUG INC. (US) | 1991-12-24 | — | — | US | disclosed |
| EP-0424850-A1 | Quinolone compounds and a process for their preparation | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1991-05-02 | — | — | EP | disclosed |
| EP-0417669-A2 | Pyridinyl-quinolone compounds, their preparation and use | STERLING WINTHROP INC. (US) | 1991-03-20 | — | — | EP | disclosed |
| US-4927926-A | BACTERICIDES | LABORATORIOS DEL DR. ESTEVE S.A. (ES) | 1990-05-22 | — | — | US | disclosed |
| EP-0309789-A1 | 4-Oxo-3-quinolinecarboxylic acids useful as antibacterial agents and preparation thereof | STERLING WINTHROP INC. (US) | 1989-04-05 | — | — | EP | disclosed |