Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.50 |
| ▸ | TOP2A | P11388 | 5/20 | 0.48 |
| ▸ | TOP2B | Q02880 | 5/20 | 0.48 |
| ▸ | STAT3 | P40763 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9693055 | 0.94 | ADRB2 (0.65) | ADRB2KCNH2TOP2ATOP2BSTAT3 | |
| SCHEMBL27442162 | 0.91 | ADRB2 (0.56) | ADRB2KCNH2TOP2ATOP2BSTAT3 | |
| SCHEMBL30944906 | 0.91 | ADRB2 (0.56) | ADRB2KCNH2TOP2ATOP2BSTAT3 | |
| SCHEMBL25669900 | 0.90 | ADRB2 (0.58) | ADRB2KCNH2TOP2ATOP2BSTAT3 | |
| SCHEMBL2844967 | 0.89 | ADRB2 (0.68) | ADRB2KCNH2TOP2ATOP2BSTAT3 | |
| SCHEMBL29492858 | 0.89 | ADRB2 (0.68) | ADRB2KCNH2TOP2ATOP2BSTAT3 | |
| SCHEMBL10627001 | 0.87 | ADRB2 (0.66) | ADRB2KCNH2TOP2ATOP2BSTAT3 | |
| SCHEMBL143605 | 0.87 | ADRB2 (0.64) | ADRB2KCNH2TOP2ATOP2BSTAT3 | |
| SCHEMBL115991 | 0.86 | ADRB2 (0.62) | ADRB2KCNH2TOP2ATOP2BSTAT3 | |
| SCHEMBL7599453 | 0.86 | ADRB2 (0.65) | ADRB2KCNH2TOP2ATOP2BSTAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2128160-B1 | Indolo[2,3-b]-, Indeno[1,2-b]- and Indeno[2,1-b]pyrido[2,3-f] quinoxaline-3-carboxylic acids and esters, processes for their preparation and their use as antiviral, antibiotic and antitumor agents | UNIV DUISBURG ESSEN (DE) | 2010-07-14 | — | — | EP | claimed |
| EP-2128160-A1 | Indolo[2,3-b]-, Indeno[1,2-b]- and Indeno[2,1-b]pyrido[2,3-f] quinoxaline-3-carboxylic acids and esters, processes for their preparation and their use as antiviral, antibiotic and antitumor agents | Universität Duisburg-Essen (DE) | 2009-12-02 | — | — | EP | claimed |
| EP-2128160-B1 | Indolo[2,3-b]-, Indeno[1,2-b]- and Indeno[2,1-b]pyrido[2,3-f] quinoxaline-3-carboxylic acids and esters, processes for their preparation and their use as antiviral, antibiotic and antitumor agents | UNIV DUISBURG ESSEN (DE) | 2010-07-14 | — | — | EP | disclosed |
| EP-2128160-A1 | Indolo[2,3-b]-, Indeno[1,2-b]- and Indeno[2,1-b]pyrido[2,3-f] quinoxaline-3-carboxylic acids and esters, processes for their preparation and their use as antiviral, antibiotic and antitumor agents | Universität Duisburg-Essen (DE) | 2009-12-02 | — | — | EP | disclosed |