SCHEMBL30945504

SCHEMBL30945504

NC(=NC(=O)Nc1cccc(Cl)c1)Nc1nc2ccccc2s1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CSNK1D P48730 2/20 0.58
HTR3E A5X5Y0 1/20 0.55
HTR3B O95264 1/20 0.55
HTR3A P46098 1/20 0.55
HTR3D Q70Z44 1/20 0.55
HTR3C Q8WXA8 1/20 0.55
DHODH Q02127 2/20 0.52
MAPT P10636 8/20 0.50
MEN1 O00255 8/20 0.50
KMT2A Q03164 8/20 0.50
RAB9A P51151 5/20 0.50
GAA P10253 4/20 0.50
NPC1 O15118 4/20 0.50
ALDH1A1 P00352 2/20 0.50
KDM4E B2RXH2 2/20 0.50
LMNA P02545 2/20 0.50
POLB P06746 2/20 0.50
HTT P42858 1/20 0.50
ATM Q13315 1/20 0.50
NFKB1 P19838 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30945509 0.87 RAB9A (0.50) CSNK1DMAPTMEN1KMT2ARAB9A
SCHEMBL30945522 0.87 SCD (0.58) MAPTMEN1KMT2ARAB9AGAA
SCHEMBL30945518 0.84 MAPT (0.55) CSNK1DDHODHMAPTMEN1KMT2A
SCHEMBL30945530 0.84 NPC1 (0.61) CSNK1DDHODHMAPTMEN1KMT2A
SCHEMBL30945490 0.84 DHODH (0.59) CSNK1DDHODHMAPTMEN1KMT2A
SCHEMBL13522371 0.83 CSNK1D (0.59) CSNK1DDHODHMAPTMEN1KMT2A
SCHEMBL13522442 0.83 CSNK1D (0.59) CSNK1DDHODHMAPTMEN1KMT2A
SCHEMBL30945526 0.83 RAB9A (0.54) CSNK1DDHODHMAPTMEN1KMT2A
SCHEMBL6225459 0.83 MAPT (0.73) CSNK1DDHODHMAPTMEN1KMT2A
SCHEMBL31206306 0.83 MAPT (0.73) CSNK1DDHODHMAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4638427-A1 AMIDINOUREA DERIVATIVES AND THEIR USE IN THE TREATMENT OF CANCER Université Côte d'Azur (FR) 2025-10-29 EP disclosed
WO-2024133857-A1 AMIDINOUREA DERIVATIVES AND THEIR USE IN THE TREATMENT OF CANCER UNIVERSITE COTE D'AZUR (FR) 2024-06-27 WO disclosed