SCHEMBL30945522

SCHEMBL30945522

Cc1cccc(NC(=O)N=C(N)Nc2nc3ccccc3s2)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SCD O00767 1/20 0.58
MAPT P10636 11/20 0.53
MEN1 O00255 8/20 0.53
KMT2A Q03164 8/20 0.53
RAB9A P51151 8/20 0.53
NPC1 O15118 7/20 0.53
SMN1; SMN2 Q16637 6/20 0.53
CYP1A2 P05177 2/20 0.53
CYP2D6 P10635 2/20 0.53
CYP3A4 P08684 1/20 0.53
CYP2C19 P33261 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
ALDH1A1 P00352 5/20 0.52
GAA P10253 3/20 0.50
LMNA P02545 3/20 0.50
POLB P06746 3/20 0.50
NFKB1 P19838 1/20 0.50
NFKB2 Q00653 1/20 0.50
RELA Q04206 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30945509 0.87 RAB9A (0.50) SCDMAPTMEN1KMT2ARAB9A
SCHEMBL30945504 0.87 CSNK1D (0.58) MAPTMEN1KMT2ARAB9ANPC1
SCHEMBL30945530 0.86 NPC1 (0.61) SCDMAPTMEN1KMT2ARAB9A
SCHEMBL30945518 0.84 MAPT (0.55) SCDMAPTMEN1KMT2ARAB9A
SCHEMBL30945502 0.83 ADORA1 (0.53) SCDMAPTMEN1KMT2ARAB9A
SCHEMBL30945511 0.83 RAB9A (0.49) MAPTMEN1KMT2ARAB9ANPC1
SCHEMBL30945515 0.83 KDM4E (0.62) SCDMAPTMEN1KMT2ARAB9A
SCHEMBL30945503 0.82 RAB9A (0.62) MAPTMEN1KMT2ARAB9ANPC1
SCHEMBL30945519 0.81 NPC1 (0.55) SCDMAPTMEN1KMT2ARAB9A
SCHEMBL30945491 0.81 NPC1 (0.53) MAPTMEN1KMT2ARAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4638427-A1 AMIDINOUREA DERIVATIVES AND THEIR USE IN THE TREATMENT OF CANCER Université Côte d'Azur (FR) 2025-10-29 EP disclosed
WO-2024133857-A1 AMIDINOUREA DERIVATIVES AND THEIR USE IN THE TREATMENT OF CANCER UNIVERSITE COTE D'AZUR (FR) 2024-06-27 WO disclosed