Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 10/20 | 0.53 |
| ▸ | RAB9A | P51151 | 10/20 | 0.53 |
| ▸ | MAPT | P10636 | 8/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.53 |
| ▸ | RELA | Q04206 | 3/20 | 0.53 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30945503 | 0.89 | RAB9A (0.62) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL30945509 | 0.88 | RAB9A (0.50) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL30945524 | 0.84 | ALDH1A1 (0.64) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL30945515 | 0.81 | KDM4E (0.62) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL30945504 | 0.81 | CSNK1D (0.58) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL30945522 | 0.81 | SCD (0.58) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL30945533 | 0.79 | RAB9A (0.57) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL30945528 | 0.79 | GAA (0.50) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL30945502 | 0.79 | ADORA1 (0.53) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL30945526 | 0.79 | RAB9A (0.54) | NPC1RAB9AMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4638427-A1 | AMIDINOUREA DERIVATIVES AND THEIR USE IN THE TREATMENT OF CANCER | Université Côte d'Azur (FR) | 2025-10-29 | — | — | EP | disclosed |
| WO-2024133857-A1 | AMIDINOUREA DERIVATIVES AND THEIR USE IN THE TREATMENT OF CANCER | UNIVERSITE COTE D'AZUR (FR) | 2024-06-27 | — | — | WO | disclosed |