Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.70 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.66 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.65 |
| ▸ | DRD2 | P14416 | 1/20 | 0.61 |
| ▸ | DRD1 | P21728 | 1/20 | 0.61 |
| ▸ | DRD4 | P21917 | 1/20 | 0.61 |
| ▸ | DRD5 | P21918 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.58 |
| ▸ | HTR1A | P08908 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL631839 | 1.00 | ACHE (0.70) | ACHECHRNA7SIGMAR1DRD2DRD1 | |
| SCHEMBL17792379 | 0.90 | ACHE (0.62) | ACHECHRNA7SIGMAR1DRD2DRD1 | |
| SCHEMBL30704370 | 0.88 | SIGMAR1 (0.70) | ACHECHRNA7SIGMAR1KDM4EALDH1A1 | |
| SCHEMBL6369610 | 0.88 | HTR1A (0.71) | SIGMAR1DRD2DRD1DRD4DRD5 | |
| SCHEMBL633048 | 0.82 | ACHE (1.00) | ACHESIGMAR1 | |
| SCHEMBL2188030 | 0.81 | ACHE (0.76) | ACHEALDH1A1LMNAMAPTBAZ2B | |
| SCHEMBL17792376 | 0.80 | ACHE (0.64) | ACHECHRNA7SIGMAR1KDM4EALDH1A1 | |
| SCHEMBL3716545 | 0.80 | BAZ2B (0.62) | ACHEBAZ2B | |
| SCHEMBL7996548 | 0.80 | BAZ2B (0.49) | ACHECHRNA7SIGMAR1DRD2DRD1 | |
| SCHEMBL168248 | 0.80 | CHRNA7 (1.00) | ACHECHRNA7SIGMAR1DRD2DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240197694-A1 | MODIFIED PROTEINS AND PROTEIN BINDERS | CULLGEN (SHANGHAI), INC. (CN) | 2024-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240197694-A1 | MODIFIED PROTEINS AND PROTEIN BINDERS | DCAF1, DDB1, CUL4A | ACHE 4434/4885CHRNA7 4675/4885SIGMAR1 4137/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.