Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.72 |
| ▸ | HTR6 | P50406 | 2/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | F2 | P00734 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.54 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30945708 | 0.90 | SMN1; SMN2 (0.73) | SMN1; SMN2HTR6ALDH1A1MAPK1MAPT | |
| SCHEMBL30945669 | 0.88 | SMN1; SMN2 (0.70) | SMN1; SMN2HTR6ALDH1A1MAPK1MAPT | |
| SCHEMBL30945695 | 0.87 | MAPT (0.67) | SMN1; SMN2HTR6ALDH1A1MAPK1MAPT | |
| SCHEMBL30945711 | 0.84 | SMN1; SMN2 (1.00) | SMN1; SMN2HTR6ALDH1A1MAPK1MAPT | |
| SCHEMBL29223991 | 0.82 | ALDH1A1 (0.67) | SMN1; SMN2HTR6ALDH1A1MAPK1MAPT | |
| SCHEMBL30945658 | 0.82 | SMN1; SMN2 (0.65) | SMN1; SMN2HTR6ALDH1A1MAPK1MAPT | |
| SCHEMBL12868610 | 0.82 | ALDH1A1 (0.70) | HTR6ALDH1A1MAPK1MAPTLMNA | |
| SCHEMBL30095965 | 0.81 | SMN1; SMN2 (0.61) | SMN1; SMN2HTR6ALDH1A1MAPK1MAPT | |
| SCHEMBL30095908 | 0.81 | SMN1; SMN2 (0.61) | SMN1; SMN2HTR6ALDH1A1MAPK1MAPT | |
| SCHEMBL13368729 | 0.80 | HTR6 (1.00) | SMN1; SMN2HTR6ALDH1A1MAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240197694-A1 | MODIFIED PROTEINS AND PROTEIN BINDERS | CULLGEN (SHANGHAI), INC. (CN) | 2024-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240197694-A1 | MODIFIED PROTEINS AND PROTEIN BINDERS | DCAF1, DDB1, CUL4A | SMN1; SMN2 3151/4885HTR6 4628/4885ALDH1A1 2985/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.