Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 3/20 | 1.00 |
| ▸ | HRH1 | P35367 | 1/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.51 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13368740 | 0.87 | HTR6 (1.00) | HTR6HRH1ALDH1A1GAAAPOBEC3A | |
| SCHEMBL12868637 | 0.81 | HTR6 (0.67) | HTR6HRH1ALDH1A1GAAAPOBEC3A | |
| SCHEMBL30945715 | 0.80 | SMN1; SMN2 (0.72) | HTR6ALDH1A1GAAAPOBEC3AAPOBEC3G | |
| SCHEMBL30095951 | 0.79 | HTR6 (0.64) | HTR6ALDH1A1GAAAPOBEC3AAPOBEC3G | |
| SCHEMBL30095888 | 0.79 | HTR6 (0.64) | HTR6ALDH1A1GAAAPOBEC3AAPOBEC3G | |
| SCHEMBL13368730 | 0.76 | HTR6 (0.60) | HTR6HRH1ALDH1A1GAAMAPT | |
| SCHEMBL12882152 | 0.74 | GAA (0.62) | HTR6ALDH1A1GAAAPOBEC3AAPOBEC3G | |
| SCHEMBL12868610 | 0.73 | ALDH1A1 (0.70) | HTR6ALDH1A1GAAAPOBEC3AAPOBEC3G | |
| SCHEMBL29223991 | 0.72 | ALDH1A1 (0.67) | HTR6ALDH1A1GAAAPOBEC3AAPOBEC3G | |
| SCHEMBL11567411 | 0.72 | ALDH1A1 (0.56) | HTR6ALDH1A1GAAAPOBEC3AAPOBEC3G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100120792-A1 | Substituted 2,3,4,5-Tetrahyrdo-1H-Pyrido[4,3-B]Indoles, Methods for the Production and Use Thereof | ALLA CHEM, LLC | 2010-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100120792-A1 | Substituted 2,3,4,5-Tetrahyrdo-1H-Pyrido[4,3-B]Indoles, Methods for the Production and Use Thereof | HTR3C, HTR3A, HTR6 | HTR6 3/4885HRH1 75/4885ALDH1A1 2039/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.