Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10375853 | 0.93 | BCHE (0.70) | SIGMAR1ACHE | |
| SCHEMBL10668586 | 0.90 | GRIN2B (0.66) | SIGMAR1 | |
| SCHEMBL10666818 | 0.84 | GRIN2B (0.75) | SIGMAR1 | |
| SCHEMBL801651 | 0.84 | SIGMAR1 (0.67) | SIGMAR1 | |
| Carvotroline SCHEMBL350602 | 0.84 | SIGMAR1 (0.88) | SIGMAR1ACHE | |
| Carvotroline SCHEMBL29710918 | 0.84 | SIGMAR1 (0.88) | SIGMAR1ACHE | |
| SCHEMBL10668365 | 0.83 | GRIN2B (0.70) | SIGMAR1 | |
| Carvotroline SCHEMBL123737 | 0.83 | SIGMAR1 (0.86) | SIGMAR1ACHE | |
| SCHEMBL10662730 | 0.82 | HTR1A (0.69) | SIGMAR1 | |
| Hydrochloric Acid SCHEMBL10667418 | 0.82 | GRIN2B (0.69) | SIGMAR1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240197694-A1 | MODIFIED PROTEINS AND PROTEIN BINDERS | CULLGEN (SHANGHAI), INC. (CN) | 2024-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240197694-A1 | MODIFIED PROTEINS AND PROTEIN BINDERS | DCAF1, DDB1, CUL4A | SIGMAR1 4137/4885ACHE 4434/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.