SCHEMBL30946204

SCHEMBL30946204

CC(=O)NCc1cc2cc(Cl)c(NCc3cscn3)cc2[nH]1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4C Q9H3R0 1/20 0.41
▸ SMN1; SMN2 Q16637 2/20 0.37
▸ MTNR1A P48039 4/20 0.34
▸ MTNR1B P49286 4/20 0.34
▸ SCN1A P35498 6/20 0.33
▸ SCN5A Q14524 6/20 0.33
▸ SCN8A Q9UQD0 6/20 0.33
▸ NPSR1 Q6W5P4 1/20 0.33
▸ MAPK1 P28482 1/20 0.33
▸ MAPT P10636 2/20 0.32
▸ ADORA2A P29274 1/20 0.32
▸ ADORA1 P30542 1/20 0.32
▸ MEN1 O00255 1/20 0.32
▸ LMNA P02545 1/20 0.32
▸ KMT2A Q03164 1/20 0.32
▸ KDM4E B2RXH2 1/20 0.32
▸ ALDH1A1 P00352 1/20 0.32
▸ HTT P42858 1/20 0.32
▸ SCN1B Q07699 1/20 0.32
▸ NOTUM Q6P988 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27247504 1.00 KDM4C (0.41) KDM4CSMN1; SMN2MTNR1AMTNR1BSCN1A
SCHEMBL27247764 0.87 KDM4C (0.37) KDM4CSMN1; SMN2SCN1ASCN5ASCN8A
SCHEMBL30920471 0.87 KDM4C (0.37) KDM4CSMN1; SMN2SCN1ASCN5ASCN8A
SCHEMBL30946226 0.85 KDM4C (0.37) KDM4CSMN1; SMN2SCN1ASCN5ASCN8A
SCHEMBL27247607 0.85 KDM4C (0.37) KDM4CSMN1; SMN2SCN1ASCN5ASCN8A
SCHEMBL30946182 0.85 KDM4C (0.37) KDM4CSMN1; SMN2SCN1ASCN5ASCN8A
SCHEMBL30946073 0.83 SMN1; SMN2 (0.39) SMN1; SMN2MTNR1AMTNR1BNPSR1
SCHEMBL27247799 0.83 LOXL2 (0.38) KDM4CSCN1ASCN5ASCN8ASCN1B
SCHEMBL31408330 0.81 SMN1; SMN2 (0.40) SMN1; SMN2MTNR1AMTNR1BNPSR1MAPT
SCHEMBL30946288 0.80 SMN1; SMN2 (0.39) SMN1; SMN2MTNR1AMTNR1BNPSR1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240199546-A1 INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF HERCULES CAPITAL, INC., AS AGENT 2024-06-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240199546-A1 INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF SLC6A19, SLC2A9, SLC6A3 KDM4C 3802/4885SMN1; SMN2 375/4885MTNR1A 158/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback