Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | KIT | P10721 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.30 |
| ▸ | METTL14 | Q9HCE5 | 1/20 | 0.30 |
| ▸ | SCD | O00767 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27247420 | 1.00 | MET (0.35) | METMAPK1KDM1AGRM5KIT | |
| SCHEMBL30946218 | 0.98 | MAPK1 (0.34) | METMAPK1KDM1AGRM5KIT | |
| SCHEMBL27247117 | 0.89 | GRM5 (0.37) | METMAPK1GRM5KITRAB9A | |
| SCHEMBL27246866 | 0.89 | MAPK1 (0.36) | METMAPK1GRM5RAB9ASCD | |
| SCHEMBL30946117 | 0.89 | GRM5 (0.37) | METMAPK1GRM5KITRAB9A | |
| SCHEMBL30946236 | 0.89 | MAPK1 (0.36) | METMAPK1GRM5RAB9ASCD | |
| SCHEMBL30920912 | 0.89 | KDM1A (0.33) | MAPK1KDM1ANPC1RAB9AMETTL3 | |
| SCHEMBL27247360 | 0.89 | KDM1A (0.33) | MAPK1KDM1ANPC1RAB9AMETTL3 | |
| SCHEMBL27247257 | 0.89 | ALK (0.34) | METMAPK1GRM5 | |
| SCHEMBL27247665 | 0.88 | EPHX2 (0.36) | METMAPK1KDM1AGRM5KIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240199546-A1 | INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF | HERCULES CAPITAL, INC., AS AGENT | 2024-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240199546-A1 | INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF | SLC6A19, SLC2A9, SLC6A3 | MET 1337/4885MAPK1 3172/4885KDM1A 3500/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.