SCHEMBL30947201

SCHEMBL30947201

O=c1[nH]ncn1-c1ccc(Br)cc1F

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
HTT P42858 1/20 0.40
AKR1B1 P15121 2/20 0.38
HCAR1 Q9BXC0 2/20 0.37
RXFP1 Q9HBX9 1/20 0.36
USP2 O75604 1/20 0.34
PKM P14618 1/20 0.34
DGAT1 O75907 1/20 0.34
ALOX15 P16050 1/20 0.34
TSHR P16473 1/20 0.34
CCR1 P32246 4/20 0.34
CCR2 P41597 4/20 0.34
HSP90AA1 P07900 1/20 0.33
HSP90B1 P14625 1/20 0.33
TRAP1 Q12931 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16196993 1.00 RAB9A (0.41) RAB9ATDP1HTTAKR1B1HCAR1
SCHEMBL21385220 0.84 HTT (0.40) RAB9ATDP1HTTAKR1B1HSP90AA1
SCHEMBL8723259 0.83 TDP1 (0.42) RAB9ATDP1HTTAKR1B1HCAR1
SCHEMBL30947126 0.81 HCAR1 (0.55) RAB9AHTTHCAR1ALOX15TSHR
SCHEMBL22206481 0.81 HCAR1 (0.55) RAB9AHTTHCAR1ALOX15TSHR
SCHEMBL21384891 0.80 HTT (0.42) RAB9ATDP1HTTAKR1B1HSP90AA1
SCHEMBL19643978 0.77 MEN1 (0.44) HCAR1RXFP1PKM
SCHEMBL21382530 0.75 HTT (0.38) RAB9ATDP1HTTAKR1B1
SCHEMBL27187357 0.74 CRBN (0.42) AKR1B1HCAR1RXFP1DGAT1ALOX15
SCHEMBL21382260 0.74 MEN1 (0.44) HTTRXFP1ALOX15TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118894816-A 3, 3-Difluoroallylamine or salt thereof and pharmaceutical composition comprising the same 柳韩洋行 2024-11-05 CN disclosed
CN-113330001-B 3, 3-Difluoroallylamine or salt thereof and pharmaceutical composition comprising the same 柳韩洋行 2024-07-02 CN disclosed