Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 7/20 | 0.50 |
| ▸ | VNN1 | O95497 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | RPLP1 | P05386 | 1/20 | 0.34 |
| ▸ | RPLP0 | P05388 | 1/20 | 0.34 |
| ▸ | RPS17 | P08708 | 1/20 | 0.34 |
| ▸ | RPSA | P08865 | 1/20 | 0.34 |
| ▸ | RPS2 | P15880 | 1/20 | 0.34 |
| ▸ | RPL35A | P18077 | 1/20 | 0.34 |
| ▸ | RPL7 | P18124 | 1/20 | 0.34 |
| ▸ | RPL17 | P18621 | 1/20 | 0.34 |
| ▸ | RPS4Y1 | P22090 | 1/20 | 0.34 |
| ▸ | RPS3 | P23396 | 1/20 | 0.34 |
| ▸ | RPS12 | P25398 | 1/20 | 0.34 |
| ▸ | RPL13 | P26373 | 1/20 | 0.34 |
| ▸ | RPL10 | P27635 | 1/20 | 0.34 |
| ▸ | RPL12 | P30050 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30361471 | 0.89 | HPGD (0.52) | HPGDVNN1RXRASMN1; SMN2ADORA2A | |
| SCHEMBL24928925 | 0.88 | HPGD (0.47) | HPGDVNN1RXRASCN9ASMN1; SMN2 | |
| SCHEMBL30361427 | 0.88 | HPGD (0.47) | HPGDVNN1RXRASCN9ASMN1; SMN2 | |
| SCHEMBL30947677 | 0.86 | HPGD (0.48) | HPGDVNN1SMN1; SMN2ADORA2ALRRK2 | |
| SCHEMBL24463691 | 0.84 | HPGD (0.53) | HPGDVNN1RXRASMN1; SMN2ADORA2A | |
| SCHEMBL30361451 | 0.84 | HPGD (0.52) | HPGDVNN1RXRAKCNH2ADORA2A | |
| SCHEMBL24928924 | 0.84 | HPGD (0.52) | HPGDVNN1RXRAKCNH2ADORA2A | |
| SCHEMBL24929885 | 0.82 | HPGD (0.51) | HPGDPRKAA2SCN9ASMN1; SMN2ADORA2A | |
| SCHEMBL24929596 | 0.81 | HPGD (0.57) | HPGDVNN1RXRAADORA2ALRRK2 | |
| SCHEMBL24928923 | 0.80 | HPGD (0.50) | HPGDVNN1RXRASMN1; SMN2ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118201926-A | Bicyclic PGDH inhibitors and methods of making and using the same | 埃皮里姆生物股份有限公司 | 2024-06-14 | — | — | CN | disclosed |