Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | CTPS1 | P17812 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 3/20 | 0.34 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30947755 | 0.84 | NPC1 (0.43) | OPRM1ALDH1A1HTTLMNASMN1; SMN2 | |
| SCHEMBL30947763 | 0.84 | ALDH1A1 (0.44) | OPRM1OPRD1OPRK1ALDH1A1HTT | |
| SCHEMBL30947765 | 0.80 | ALDH1A1 (0.39) | OPRM1OPRD1OPRK1ALDH1A1HTT | |
| SCHEMBL28528143 | 0.77 | MAPT (0.43) | OPRM1OPRD1OPRK1ALDH1A1HTT | |
| SCHEMBL30947752 | 0.77 | MAPT (0.43) | OPRM1OPRD1OPRK1ALDH1A1HTT | |
| SCHEMBL28528146 | 0.77 | MAPT (0.43) | OPRM1OPRD1OPRK1ALDH1A1HTT | |
| SCHEMBL28528144 | 0.77 | MAPT (0.43) | OPRM1OPRD1OPRK1ALDH1A1HTT | |
| SCHEMBL6571203 | 0.72 | MAPT (0.54) | OPRM1OPRD1OPRK1ALDH1A1HTT | |
| SCHEMBL30947732 | 0.70 | GFER (0.39) | OPRM1OPRD1OPRK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL28907761 | 0.70 | GFER (0.39) | OPRM1OPRD1OPRK1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112469707-B | Preventive or therapeutic agent for spinal muscular atrophy | 利伯纳生物科学株式会社 | 2024-06-21 | — | — | CN | disclosed |