Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 2/20 | 0.38 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | CTPS1 | P17812 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3435480 | 0.80 | MAPT (0.48) | ALDH1A1SMN1; SMN2PARP1LMNAMAPT | |
| SCHEMBL30947762 | 0.80 | OPRM1 (0.40) | ALDH1A1SMN1; SMN2OPRM1OPRD1OPRK1 | |
| SCHEMBL6571203 | 0.76 | MAPT (0.54) | ALDH1A1SMN1; SMN2OPRM1OPRD1OPRK1 | |
| SCHEMBL24663014 | 0.74 | SIRT6 (0.49) | ALDH1A1SMN1; SMN2HTTLMNAMAPT | |
| SCHEMBL28533396 | 0.74 | SIRT6 (0.49) | ALDH1A1SMN1; SMN2HTTLMNAMAPT | |
| SCHEMBL24662997 | 0.74 | SIRT6 (0.49) | ALDH1A1SMN1; SMN2HTTLMNAMAPT | |
| SCHEMBL30947763 | 0.74 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2OPRM1OPRD1OPRK1 | |
| SCHEMBL5789102 | 0.73 | POLB (0.44) | ALDH1A1SMN1; SMN2LMNAMAPTMEN1 | |
| SCHEMBL31729425 | 0.70 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2LMNAMAPTMEN1 | |
| SCHEMBL28086239 | 0.70 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2LMNAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112469707-B | Preventive or therapeutic agent for spinal muscular atrophy | 利伯纳生物科学株式会社 | 2024-06-21 | — | — | CN | disclosed |