Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.88 |
| ▸ | TP53 | P04637 | 1/20 | 0.88 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.88 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.88 |
| ▸ | TSHR | P16473 | 1/20 | 0.88 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.88 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.88 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.88 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.88 |
| ▸ | SLC22A1 | O15245 | 4/20 | 0.81 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.75 |
| ▸ | DNM1 | Q05193 | 6/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL5087513 | 1.00 | ALDH1A1 (0.88) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| Bromide SCHEMBL5091659 | 1.00 | ALDH1A1 (0.88) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| Bromide SCHEMBL5087895 | 1.00 | ALDH1A1 (0.88) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| Bromide SCHEMBL892744 | 1.00 | ALDH1A1 (0.88) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| Bromide SCHEMBL5087153 | 1.00 | ALDH1A1 (0.88) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| Bromide SCHEMBL5086882 | 1.00 | ALDH1A1 (0.88) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| Bromide SCHEMBL5085129 | 1.00 | ALDH1A1 (0.88) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| Bromide SCHEMBL5086923 | 1.00 | ALDH1A1 (0.88) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| Bromide SCHEMBL3087580 | 1.00 | ALDH1A1 (0.88) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| Bromide SCHEMBL5091866 | 1.00 | ALDH1A1 (0.88) | ALDH1A1TP53CYP3A4ALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8653293-B2 | Mobile self-spreading biocides | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2014-02-18 | — | — | US | disclosed |
| US-20130123531-A1 | Mobile Self-Spreading Biocides | THE GOVERNMENT OF THE UNITED STATES, AS RESPRESENTED BY THE SECRETARY OF THE NAVY | 2013-05-16 | — | — | US | disclosed |
| US-8362290-B2 | Mobile self-spreading biocides | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2013-01-29 | — | — | US | disclosed |
| US-20100227837-A1 | Mobile Self-Spreading Biocides | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2010-09-09 | — | — | US | disclosed |
| US-7741503-B2 | Mobile self-spreading biocides | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2010-06-22 | — | — | US | disclosed |
| US-20080076938-A1 | MOBILE SELF-SPREADING BIOCIDES | THE GOVERNMENT OF THE US, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2008-03-27 | — | — | US | disclosed |
| US-4247342-A | Method and composition for removing ethylene glycol terephthalate oligomer deposits and dyestuff residue from textile dyeing equipment | MILLIKEN RESEARCH CORPORATION (US) | 1981-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080076938-A1 | MOBILE SELF-SPREADING BIOCIDES | C1S, SLC43A1, BAP1 | ALDH1A1 3562/4885TP53 1704/4885CYP3A4 2156/4885 |
| US-20100227837-A1 | Mobile Self-Spreading Biocides | C1S, SLC43A1, BAP1 | ALDH1A1 3562/4885TP53 1704/4885CYP3A4 2156/4885 |
| US-20130123531-A1 | Mobile Self-Spreading Biocides | C1S, SLC43A1, BAP1 | ALDH1A1 3596/4885TP53 1790/4885CYP3A4 2090/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.