Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.88 |
| ▸ | TP53 | P04637 | 1/20 | 0.88 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.88 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.88 |
| ▸ | TSHR | P16473 | 1/20 | 0.88 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.88 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.88 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.88 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.88 |
| ▸ | SLC22A1 | O15245 | 4/20 | 0.81 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.75 |
| ▸ | DNM1 | Q05193 | 6/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL5087513 | 1.00 | ALDH1A1 (0.88) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| Bromide SCHEMBL3094792 | 1.00 | ALDH1A1 (0.88) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| Bromide SCHEMBL5091659 | 1.00 | ALDH1A1 (0.88) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| Bromide SCHEMBL5087895 | 1.00 | ALDH1A1 (0.88) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| Bromide SCHEMBL5087153 | 1.00 | ALDH1A1 (0.88) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| Bromide SCHEMBL5086882 | 1.00 | ALDH1A1 (0.88) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| Bromide SCHEMBL5085129 | 1.00 | ALDH1A1 (0.88) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| Bromide SCHEMBL5086923 | 1.00 | ALDH1A1 (0.88) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| Bromide SCHEMBL3087580 | 1.00 | ALDH1A1 (0.88) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| Bromide SCHEMBL5091866 | 1.00 | ALDH1A1 (0.88) | ALDH1A1TP53CYP3A4ALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 179 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114685274-A | Esterification method for preparing 4-methyl chloroacetoacetate | 江西迪赛诺制药有限公司 | 2022-07-01 | — | — | CN | claimed |
| WO-2007062462-A1 | METHOD FOR ADMINISTERING A SKIN NECROSIS COMPOSITION TO AN ANIMAL | AUSTRALIAN WOOL INNOVATION LIMITED (AU) | 2007-06-07 | — | — | WO | claimed |
| US-4215076-A | BASE CATALYST, SURFACTANT CATALYST | UNION CARBIDE CORPORATION (US) | 1980-07-29 | — | — | US | claimed |
| US-4069384-A | CYCLIC ANHYDRIDE; QUATERNARY AMMONIUM SALTS OR HALOGEN ACID SALTS AS CATALYSTS | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1978-01-17 | — | — | US | claimed |
| US-12529977-B2 | Image forming apparatus and process cartridge | CANON KABUSHIKI KAISHA (JP) | 2026-01-20 | — | — | US | disclosed |
| US-20260016769-A1 | CHARGING MEMBERS | HEWLETT PACKARD DEVELOPMENT CO (US) | 2026-01-15 | — | — | US | disclosed |
| WO-2025122139-A1 | CHARGING MEMBER HAVING A SURFACE LAYER WITH WAVINESS | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) | 2025-06-12 | — | — | WO | disclosed |
| CN-119585680-A | Charging member | 惠普发展公司，有限责任合伙企业 | 2025-03-07 | — | — | CN | disclosed |
| US-20240427260-A1 | IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE | CANON KABUSHIKI KAISHA (JP) | 2024-12-26 | — | — | US | disclosed |
| EP-4481503-A1 | IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE | CANON KABUSHIKI KAISHA (JP) | 2024-12-25 | — | — | EP | disclosed |
| CN-113454090-B | Compounds having a polycyclic aromatic skeleton and endoperoxide compounds thereof | 川崎化成工业株式会社 | 2024-08-23 | — | — | CN | disclosed |
| US-12065521-B2 | Compound having polycyclic aromatic skeleton, and endoperoxide compound of same | KAWASAKI KASEI CHEMICALS LTD. (JP) | 2024-08-20 | — | — | US | disclosed |
| US-4303408-A | EXTRACTION ZONE BEFORE INDICATOR ZONE | EASTMAN KODAK COMPANY (US) | 1981-12-01 | — | — | US | disclosed |
| EP-0033707-A1 | Element for liquid analysis having interferent-removal zone and method for using same | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1981-08-12 | — | — | EP | disclosed |
| EP-0030503-A1 | Buffer overcoat for CO2 ion-selective electrodes | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1981-06-17 | — | — | EP | disclosed |
| US-4272328-A | MULTILAYER, METALS, METAL HALIDES | EASTMAN KODAK COMPANY (US) | 1981-06-09 | — | — | US | disclosed |
| US-4250255-A | IONIC AMPHIPHILE | EASTMAN KODAK COMPANY (US) | 1981-02-10 | — | — | US | disclosed |
| US-4215076-A | BASE CATALYST, SURFACTANT CATALYST | UNION CARBIDE CORPORATION (US) | 1980-07-29 | — | — | US | disclosed |
| US-4069384-A | CYCLIC ANHYDRIDE; QUATERNARY AMMONIUM SALTS OR HALOGEN ACID SALTS AS CATALYSTS | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1978-01-17 | — | — | US | disclosed |
| US-4062812-A | QUATERNARY AMMONIUM OR PHOSPHONIUM SALT | XEROX CORPORATION (US) | 1977-12-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260016769-A1 | CHARGING MEMBERS | SLIRP, SMC4, SMC1A | ALDH1A1 3002/4885TP53 3508/4885CYP3A4 4222/4885 |
| US-12529977-B2 | Image forming apparatus and process cartridge | ERCC1, EMC2, EMC1 | ALDH1A1 4449/4885TP53 4186/4885CYP3A4 4810/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.