Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.59 |
| ▸ | HPGD | P15428 | 5/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA3 | P07451 | 1/20 | 0.51 |
| ▸ | CA6 | P23280 | 1/20 | 0.51 |
| ▸ | CA5A | P35218 | 1/20 | 0.51 |
| ▸ | CA7 | P43166 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.51 |
| ▸ | GUSB | P08236 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2441042 | 0.84 | ALDH1A1 (0.57) | ALDH1A1HPGDKDM4EHSD17B10TDP1 | |
| SCHEMBL18611243 | 0.84 | ALDH1A1 (0.57) | ALDH1A1HPGDKDM4EHSD17B10TDP1 | |
| SCHEMBL30948356 | 0.82 | ALDH1A1 (0.56) | ALDH1A1HPGDKDM4EHSD17B10L3MBTL1 | |
| SCHEMBL10612164 | 0.81 | ALDH1A1 (0.38) | ALDH1A1HPGDKDM4EHSD17B10CA12 | |
| SCHEMBL9848132 | 0.77 | ALDH1A1 (0.67) | ALDH1A1HPGDKDM4EHSD17B10TDP1 | |
| SCHEMBL20864389 | 0.76 | HDAC6 (0.48) | ALDH1A1CA1CA2CA5ACA5B | |
| SCHEMBL2447703 | 0.75 | PTPN11 (0.45) | ALDH1A1HPGDKDM4EHSD17B10CA12 | |
| SCHEMBL11326692 | 0.74 | KDM4E (1.00) | ALDH1A1HPGDKDM4EHSD17B10L3MBTL1 | |
| SCHEMBL21065048 | 0.74 | ALDH1A1 (0.62) | ALDH1A1HPGDKDM4EHSD17B10CA12 | |
| SCHEMBL970693 | 0.74 | ALDH1A1 (0.62) | ALDH1A1HPGDKDM4EHSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240246937-A1 | IL4I1 INHIBITORS AND METHODS OF USE | MERCK SHARP & DOHME LLC (US) | 2024-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240246937-A1 | IL4I1 INHIBITORS AND METHODS OF USE | IL4I1, IL4, IL2 | ALDH1A1 283/4885HPGD 2021/4885KDM4E 1134/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.