Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL4I1 | Q96RQ9 | 5/20 | 0.61 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.45 |
| ▸ | HPGDS | O60760 | 7/20 | 0.39 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.37 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | DHPS | P49366 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30947938 | 0.82 | IL4I1 (0.60) | IL4I1PDE1CNPSR1PDE4APDE4B | |
| SCHEMBL27163163 | 0.80 | IL4I1 (0.59) | IL4I1KDM4ENPSR1PDE4APDE4B | |
| SCHEMBL30948039 | 0.79 | IL4I1 (0.63) | IL4I1CYP11B1PDE1C | |
| SCHEMBL30948301 | 0.78 | IL4I1 (0.63) | IL4I1CYP11B1PDE1CMAPT | |
| SCHEMBL30947964 | 0.78 | IL4I1 (0.54) | IL4I1MEN1KMT2A | |
| SCHEMBL30948348 | 0.77 | IL4I1 (0.62) | IL4I1CYP11B1NPSR1 | |
| SCHEMBL27163598 | 0.77 | IL4I1 (0.75) | IL4I1HSD17B13KDM4E | |
| SCHEMBL30947951 | 0.76 | IL4I1 (1.00) | IL4I1CYP11B1 | |
| SCHEMBL30047237 | 0.75 | IL4I1 (0.64) | IL4I1CYP11B1MEN1KMT2A | |
| SCHEMBL30948103 | 0.75 | IL4I1 (0.50) | IL4I1CYP11B1HPGDSHSD17B13PDE1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240246937-A1 | IL4I1 INHIBITORS AND METHODS OF USE | MERCK SHARP & DOHME LLC (US) | 2024-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240246937-A1 | IL4I1 INHIBITORS AND METHODS OF USE | IL4I1, IL4, IL2 | IL4I1 1/4885CYP11B1 1150/4885HPGDS 2379/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.