SCHEMBL30948898

SCHEMBL30948898

Fc1ccccc1CNc1nc(Cl)nn2c(Cl)ccc12

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
TP53 P04637 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
POLB P06746 1/20 0.43
GAA P10253 1/20 0.43
CYP1A2 P05177 2/20 0.43
CYP2C9 P11712 2/20 0.43
CYP2C19 P33261 2/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
ALDH1A1 P00352 1/20 0.43
HPGD P15428 1/20 0.43
ADORA3 P0DMS8 2/20 0.42
ADORA1 P30542 2/20 0.42
MAPT P10636 1/20 0.41
ATM Q13315 1/20 0.41
PLA2G1B P04054 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
ATG4B Q9Y4P1 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30948908 0.88 TP53 (0.44) MEN1KMT2ATP53SMN1; SMN2POLB
SCHEMBL30948887 0.88 MEN1 (0.42) MEN1KMT2ATP53SMN1; SMN2POLB
SCHEMBL30948905 0.81 PDE5A (0.51) KMT2ATP53ALDH1A1HPGDMAPT
SCHEMBL30948881 0.79 RXFP1 (0.44) MEN1KMT2ATP53HPGDMAPT
SCHEMBL31057965 0.74 SMN1; SMN2 (0.49) MEN1KMT2ATP53SMN1; SMN2POLB
SCHEMBL31030139 0.74 SMN1; SMN2 (0.49) MEN1KMT2ASMN1; SMN2GAACYP1A2
SCHEMBL2032760 0.72 L3MBTL1 (0.54) MEN1KMT2ATP53SMN1; SMN2POLB
SCHEMBL30997392 0.72 KCNH3 (0.41) TP53SMN1; SMN2POLBGAAMAPT
SCHEMBL31010601 0.71 TLR7 (0.37) SMN1; SMN2
SCHEMBL31010620 0.71 HRH4 (0.41) SMN1; SMN2CYP2C19ADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4651949-A1 COMPOSITIONS USEFUL FOR MODULATING SPLICING Skyhawk Therapeutics, Inc. (US) 2025-11-26 EP disclosed
WO-2024155834-A1 COMPOSITIONS USEFUL FOR MODULATING SPLICING SKYHAWK THERAPEUTICS, INC. (US) 2024-07-25 WO disclosed