Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 4/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | BCDIN3D | Q7Z5W3 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.30 |
| ▸ | TGFBR2 | P37173 | 2/20 | 0.30 |
| ▸ | BUB1 | O43683 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 2/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30997372 | 0.86 | KCNH3 (0.41) | KCNH3LOXL2TGFBR1BUB1 | |
| SCHEMBL30948908 | 0.85 | TP53 (0.44) | PDE2APOLBTP53GAASMN1; SMN2 | |
| SCHEMBL30997374 | 0.81 | PDE10A (0.43) | KDRTGFBR1PDE2APOLBMAPT | |
| SCHEMBL30997378 | 0.77 | KCNH3 (0.38) | KCNH3EGFRKDRNAMPTPDE2A | |
| SCHEMBL30997381 | 0.76 | KCNH3 (0.40) | KCNH3LOXL2TGFBR1BCDIN3DTGFBR2 | |
| SCHEMBL30948919 | 0.74 | APP (0.49) | TP53MAPT | |
| SCHEMBL30948898 | 0.72 | MEN1 (0.43) | PDE2APOLBTP53GAASMN1; SMN2 | |
| SCHEMBL31010604 | 0.72 | TLR7 (0.36) | EGFRKDRSMN1; SMN2 | |
| SCHEMBL31010597 | 0.72 | HRH4 (0.41) | SMN1; SMN2 | |
| SCHEMBL30948887 | 0.71 | MEN1 (0.42) | PDE2APOLBTP53GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4651950-A1 | COMPOSITIONS USEFUL FOR MODULATING SPLICING | Skyhawk Therapeutics, Inc. (US) | 2025-11-26 | — | — | EP | disclosed |
| WO-2024155842-A1 | COMPOSITIONS USEFUL FOR MODULATING SPLICING | SKYHAWK THERAPEUTICS, INC. (US) | 2024-07-25 | — | — | WO | disclosed |