Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.49 |
| ▸ | PDE5A | O76074 | 1/20 | 0.49 |
| ▸ | CDK1 | P06493 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
| ▸ | PLK1 | P53350 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | UBE2N | P61088 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30997374 | 0.88 | PDE10A (0.43) | APPPDE5ACDK1KDM4EALDH1A1 | |
| SCHEMBL30948905 | 0.86 | PDE5A (0.51) | APPPDE5ACDK1KDM4EALDH1A1 | |
| SCHEMBL30948921 | 0.84 | PDE5A (0.49) | APPPDE5ACDK1KDM4EALDH1A1 | |
| SCHEMBL31487322 | 0.83 | PDE5A (0.48) | APPPDE5ACDK1ALDH1A1HPGD | |
| SCHEMBL30948908 | 0.82 | TP53 (0.44) | KDM4EALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL31487162 | 0.82 | CDK1 (0.46) | APPPDE5ACDK1KDM4EPDE10A | |
| SCHEMBL31487047 | 0.81 | APP (0.44) | APPPDE5ACDK1KDM4EALDH1A1 | |
| SCHEMBL31487219 | 0.81 | APP (0.44) | APPPDE5ACDK1KDM4EALDH1A1 | |
| SCHEMBL31487415 | 0.81 | PDE5A (0.46) | APPPDE5ACDK1KDM4EALDH1A1 | |
| SCHEMBL31487263 | 0.79 | F2 (0.45) | APPPDE5ACDK1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4651949-A1 | COMPOSITIONS USEFUL FOR MODULATING SPLICING | Skyhawk Therapeutics, Inc. (US) | 2025-11-26 | — | — | EP | disclosed |
| WO-2024155834-A1 | COMPOSITIONS USEFUL FOR MODULATING SPLICING | SKYHAWK THERAPEUTICS, INC. (US) | 2024-07-25 | — | — | WO | disclosed |