Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PGK1 | P00558 | 1/20 | 0.37 |
| ▸ | FLT1 | P17948 | 2/20 | 0.37 |
| ▸ | KDR | P35968 | 2/20 | 0.37 |
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.36 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30948919 | 0.88 | APP (0.49) | PDE10AALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL30997378 | 0.83 | KCNH3 (0.38) | ALDH1A1KDM4ELMNAMAPTKDR | |
| SCHEMBL30997392 | 0.81 | KCNH3 (0.41) | POLBTGFBR1MAPTKDRPDE2A | |
| SCHEMBL31010597 | 0.78 | HRH4 (0.41) | PDE10AADORA2AADORA1CHRM4 | |
| SCHEMBL31010604 | 0.78 | TLR7 (0.36) | KDR | |
| SCHEMBL30948908 | 0.76 | TP53 (0.44) | POLBL3MBTL1ALDH1A1KDM4EMAPT | |
| SCHEMBL31010619 | 0.76 | PDE10A (0.46) | PDE10A | |
| SCHEMBL30997380 | 0.76 | EGFR (0.45) | PDE10APOLBL3MBTL1ADRA2CALDH1A1 | |
| SCHEMBL18414929 | 0.75 | TGFBR1 (0.57) | PDE10APOLBL3MBTL1TGFBR1ALDH1A1 | |
| SCHEMBL30948905 | 0.74 | PDE5A (0.51) | PDE10AALDH1A1KDM4ELMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4651950-A1 | COMPOSITIONS USEFUL FOR MODULATING SPLICING | Skyhawk Therapeutics, Inc. (US) | 2025-11-26 | — | — | EP | disclosed |
| WO-2024155842-A1 | COMPOSITIONS USEFUL FOR MODULATING SPLICING | SKYHAWK THERAPEUTICS, INC. (US) | 2024-07-25 | — | — | WO | disclosed |