Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 3/20 | 0.48 |
| ▸ | APP | P05067 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 3/20 | 0.45 |
| ▸ | CDK1 | P06493 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GBA1 | P04062 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | PLK1 | P53350 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAT2A | P31153 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31487103 | 0.89 | PDE5A (0.43) | PDE5AAPPESR1CDK1TP53 | |
| SCHEMBL30948905 | 0.85 | PDE5A (0.51) | PDE5AAPPESR1CDK1TP53 | |
| SCHEMBL30948919 | 0.83 | APP (0.49) | PDE5AAPPESR1CDK1TP53 | |
| SCHEMBL30948921 | 0.83 | PDE5A (0.49) | PDE5AAPPESR1CDK1TP53 | |
| SCHEMBL31487415 | 0.80 | PDE5A (0.46) | PDE5AAPPESR1CDK1RXFP1 | |
| SCHEMBL26605845 | 0.80 | CDK1 (0.50) | PDE5AAPPESR1CDK1TP53 | |
| SCHEMBL31487162 | 0.79 | CDK1 (0.46) | PDE5AAPPESR1CDK1MAPT | |
| SCHEMBL31487219 | 0.78 | APP (0.44) | PDE5AAPPESR1CDK1ATM | |
| SCHEMBL31487285 | 0.78 | MAPT (0.44) | PDE5AAPPCDK1KMT2AMEN1 | |
| SCHEMBL31487047 | 0.78 | APP (0.44) | PDE5AAPPESR1CDK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025074096-A1 | P97 (VCP) ATPASE INHIBITORS | Turbine Simulated Cell Technologies Ltd (GB) | 2025-04-10 | — | — | WO | disclosed |