Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 6/20 | 0.46 |
| ▸ | APP | P05067 | 2/20 | 0.45 |
| ▸ | PDE5A | O76074 | 1/20 | 0.45 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 2/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.38 |
| ▸ | CDK7 | P50613 | 1/20 | 0.38 |
| ▸ | CDK9 | P50750 | 1/20 | 0.38 |
| ▸ | CCNH | P51946 | 1/20 | 0.38 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.38 |
| ▸ | USP1 | O94782 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30948919 | 0.82 | APP (0.49) | CDK1APPPDE5APDE10ABCHE | |
| SCHEMBL30948905 | 0.82 | PDE5A (0.51) | CDK1APPPDE5APDE10AESR1 | |
| SCHEMBL30948921 | 0.80 | PDE5A (0.49) | CDK1APPPDE5APDE10AESR1 | |
| SCHEMBL31487047 | 0.80 | APP (0.44) | CDK1APPPDE5APDE10ABCHE | |
| SCHEMBL31487219 | 0.80 | APP (0.44) | CDK1APPPDE5AACHEESR1 | |
| SCHEMBL31487322 | 0.79 | PDE5A (0.48) | CDK1APPPDE5AESR1MAPT | |
| SCHEMBL31487263 | 0.78 | F2 (0.45) | CDK1APPPDE5AACHEKDM4E | |
| SCHEMBL31487415 | 0.77 | PDE5A (0.46) | CDK1APPPDE5AESR1KDM4E | |
| SCHEMBL31487285 | 0.75 | MAPT (0.44) | CDK1APPPDE5AKDM4EMAPT | |
| SCHEMBL31487103 | 0.74 | PDE5A (0.43) | CDK1APPPDE5AESR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025074096-A1 | P97 (VCP) ATPASE INHIBITORS | Turbine Simulated Cell Technologies Ltd (GB) | 2025-04-10 | — | — | WO | disclosed |