Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT8 | Q9H7Z6 | 5/20 | 0.38 |
| ▸ | KAT5 | Q92993 | 2/20 | 0.38 |
| ▸ | KAT6A | Q92794 | 3/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.34 |
| ▸ | CDK9 | P50750 | 3/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.33 |
| ▸ | TTK | P33981 | 2/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | F13A1 | P00488 | 1/20 | 0.33 |
| ▸ | TGM2 | P21980 | 1/20 | 0.33 |
| ▸ | TGM1 | P22735 | 1/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | MC4R | P32245 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31634671 | 1.00 | KAT8 (0.38) | KAT8KAT5KAT6ASYKPIK3R1 | |
| SCHEMBL31634688 | 0.87 | PIM1 (0.32) | SYKCDK9CCNT1DDB1CRBN | |
| SCHEMBL30948989 | 0.87 | PIM1 (0.32) | SYKCDK9CCNT1DDB1CRBN | |
| SCHEMBL31634680 | 0.84 | MC4R (0.46) | DDB1CRBNF13A1TGM2TGM1 | |
| SCHEMBL30948967 | 0.84 | MC4R (0.46) | DDB1CRBNF13A1TGM2TGM1 | |
| SCHEMBL30948968 | 0.84 | MC4R (0.46) | DDB1CRBNF13A1TGM2TGM1 | |
| SCHEMBL31634709 | 0.84 | MC4R (0.40) | SYKDDB1CRBNF13A1TGM2 | |
| SCHEMBL30948978 | 0.83 | TTK (0.42) | TTK | |
| SCHEMBL31634705 | 0.83 | TTK (0.42) | TTK | |
| SCHEMBL30948963 | 0.82 | MC4R (0.38) | DDB1CRBNF13A1TGM2TGM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024104452-A1 | MC4R ANTAGONIST COMPOUND, PHARMACEUTICAL COMPOSITION AND PHARMACEUTICAL USE THEREOF | 长春金赛药业有限责任公司 | 2024-05-23 | — | — | WO | disclosed |