Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 4/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 6/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 6/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | F13A1 | P00488 | 1/20 | 0.33 |
| ▸ | TGM2 | P21980 | 1/20 | 0.33 |
| ▸ | TGM1 | P22735 | 1/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 2/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30948968 | 1.00 | MC4R (0.46) | MC4RGPR119HCRTR1HCRTR2DDB1 | |
| SCHEMBL31634680 | 1.00 | MC4R (0.46) | MC4RGPR119HCRTR1HCRTR2DDB1 | |
| SCHEMBL31634709 | 0.88 | MC4R (0.40) | MC4RGPR119DDB1CRBNF13A1 | |
| SCHEMBL30948963 | 0.87 | MC4R (0.38) | MC4RDDB1CRBNKCNH2F13A1 | |
| SCHEMBL31634661 | 0.87 | MC4R (0.38) | MC4RDDB1CRBNKCNH2F13A1 | |
| SCHEMBL31634671 | 0.84 | KAT8 (0.38) | MC4RDDB1CRBNF13A1TGM2 | |
| SCHEMBL30948962 | 0.84 | KAT8 (0.38) | MC4RDDB1CRBNF13A1TGM2 | |
| SCHEMBL31634705 | 0.83 | TTK (0.42) | GPR119 | |
| SCHEMBL30948978 | 0.83 | TTK (0.42) | GPR119 | |
| SCHEMBL31634663 | 0.83 | MC4R (0.47) | MC4RDDB1CRBNKCNH2MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024104452-A1 | MC4R ANTAGONIST COMPOUND, PHARMACEUTICAL COMPOSITION AND PHARMACEUTICAL USE THEREOF | 长春金赛药业有限责任公司 | 2024-05-23 | — | — | WO | disclosed |