Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.37 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.36 |
| ▸ | F13A1 | P00488 | 1/20 | 0.35 |
| ▸ | TGM2 | P21980 | 1/20 | 0.35 |
| ▸ | TGM1 | P22735 | 1/20 | 0.35 |
| ▸ | IDH1 | O75874 | 2/20 | 0.35 |
| ▸ | IDH2 | P48735 | 1/20 | 0.35 |
| ▸ | EIF2AK4 | Q9P2K8 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30948970 | 0.88 | MC4R (0.36) | MC4RDDB1CRBNMMP12ACHE | |
| SCHEMBL31634713 | 0.88 | GPR119 (0.36) | DDB1CRBNMMP12ACHEGPR119 | |
| SCHEMBL31634715 | 0.88 | MC4R (0.36) | MC4RDDB1CRBNMMP12ACHE | |
| SCHEMBL30948967 | 0.88 | MC4R (0.46) | MC4RDDB1CRBNMMP12GPR119 | |
| SCHEMBL30948968 | 0.88 | MC4R (0.46) | MC4RDDB1CRBNMMP12GPR119 | |
| SCHEMBL31634680 | 0.88 | MC4R (0.46) | MC4RDDB1CRBNMMP12GPR119 | |
| SCHEMBL31634661 | 0.86 | MC4R (0.38) | MC4RDDB1CRBNMMP12F13A1 | |
| SCHEMBL30948963 | 0.86 | MC4R (0.38) | MC4RDDB1CRBNMMP12F13A1 | |
| SCHEMBL31634671 | 0.84 | KAT8 (0.38) | MC4RDDB1CRBNMMP12F13A1 | |
| SCHEMBL30948962 | 0.84 | KAT8 (0.38) | MC4RDDB1CRBNMMP12F13A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120202199-A | MC4R antagonist compound, pharmaceutical composition and application thereof in medicine | 长春金赛药业有限责任公司 | 2025-06-24 | — | — | CN | disclosed |