Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 8/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.38 |
| ▸ | MMP12 | P39900 | 1/20 | 0.32 |
| ▸ | IDH1 | O75874 | 2/20 | 0.32 |
| ▸ | IDH2 | P48735 | 1/20 | 0.32 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.32 |
| ▸ | F13A1 | P00488 | 1/20 | 0.32 |
| ▸ | TGM2 | P21980 | 1/20 | 0.32 |
| ▸ | TGM1 | P22735 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | TYK2 | P29597 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31634661 | 1.00 | MC4R (0.38) | MC4RKCNH2MMP12IDH1IDH2 | |
| SCHEMBL31634663 | 0.89 | MC4R (0.47) | MC4RKCNH2MMP12IDH1IDH2 | |
| SCHEMBL30948967 | 0.87 | MC4R (0.46) | MC4RKCNH2MMP12DDB1CRBN | |
| SCHEMBL31634680 | 0.87 | MC4R (0.46) | MC4RKCNH2MMP12DDB1CRBN | |
| SCHEMBL30948968 | 0.87 | MC4R (0.46) | MC4RKCNH2MMP12DDB1CRBN | |
| SCHEMBL31634709 | 0.86 | MC4R (0.40) | MC4RMMP12IDH1IDH2DDB1 | |
| SCHEMBL31634688 | 0.84 | PIM1 (0.32) | MC4RKCNH2MMP12IDH1IDH2 | |
| SCHEMBL30948989 | 0.84 | PIM1 (0.32) | MC4RKCNH2MMP12IDH1IDH2 | |
| SCHEMBL31634705 | 0.82 | TTK (0.42) | — | |
| SCHEMBL30948978 | 0.82 | TTK (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024104452-A1 | MC4R ANTAGONIST COMPOUND, PHARMACEUTICAL COMPOSITION AND PHARMACEUTICAL USE THEREOF | 长春金赛药业有限责任公司 | 2024-05-23 | — | — | WO | disclosed |