Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 12/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.46 |
| ▸ | IDH1 | O75874 | 2/20 | 0.32 |
| ▸ | IDH2 | P48735 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.32 |
| ▸ | TRPV3 | Q8NET8 | 2/20 | 0.31 |
| ▸ | MMP12 | P39900 | 1/20 | 0.31 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.30 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.30 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31634661 | 0.89 | MC4R (0.38) | MC4RKCNH2IDH1IDH2JAK2 | |
| SCHEMBL30948963 | 0.89 | MC4R (0.38) | MC4RKCNH2IDH1IDH2JAK2 | |
| SCHEMBL31634715 | 0.84 | MC4R (0.36) | MC4RKCNH2IDH1IDH2MMP12 | |
| SCHEMBL30948970 | 0.84 | MC4R (0.36) | MC4RKCNH2IDH1IDH2MMP12 | |
| SCHEMBL31634680 | 0.83 | MC4R (0.46) | MC4RKCNH2JAK2MMP12DDB1 | |
| SCHEMBL30948967 | 0.83 | MC4R (0.46) | MC4RKCNH2JAK2MMP12DDB1 | |
| SCHEMBL30948968 | 0.83 | MC4R (0.46) | MC4RKCNH2JAK2MMP12DDB1 | |
| SCHEMBL31634709 | 0.83 | MC4R (0.40) | MC4RIDH1IDH2MMP12DDB1 | |
| SCHEMBL31421655 | 0.83 | MC4R (0.64) | MC4RKCNH2IDH1 | |
| SCHEMBL30996531 | 0.83 | MC4R (0.64) | MC4RKCNH2IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120202199-A | MC4R antagonist compound, pharmaceutical composition and application thereof in medicine | 长春金赛药业有限责任公司 | 2025-06-24 | — | — | CN | disclosed |