Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MARS1 | P56192 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.46 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | RPA1 | P27694 | 1/20 | 0.41 |
| ▸ | UGCG | Q16739 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25078248 | 1.00 | MARS1 (0.50) | MARS1TP53MAPK14MAPK11ADORA3 | |
| SCHEMBL30949266 | 0.87 | MAPK14 (0.45) | MARS1TP53MAPK14MAPK11ADORA3 | |
| SCHEMBL30202478 | 0.87 | MAPK14 (0.48) | MARS1TP53MAPK14MAPK11PTGS1 | |
| SCHEMBL25077935 | 0.87 | MAPK14 (0.48) | MARS1TP53MAPK14MAPK11PTGS1 | |
| SCHEMBL6173365 | 0.80 | MARS1 (0.56) | MARS1TP53MAPK14ADORA3ADORA1 | |
| SCHEMBL25078603 | 0.79 | ADORA3 (0.43) | MAPK14MAPK11ADORA3ADORA1ADORA2A | |
| SCHEMBL25431512 | 0.79 | RORC (0.40) | MARS1PTGS1PTGS2KMT2AKDM4E | |
| SCHEMBL25077983 | 0.78 | MAPK14 (0.43) | MAPK14MAPK11MGLLNPSR1ALDH1A1 | |
| SCHEMBL30202561 | 0.78 | MAPK14 (0.43) | MAPK14MAPK11MGLLNPSR1ALDH1A1 | |
| SCHEMBL6173680 | 0.77 | MARS1 (0.53) | MARS1MAPK14ALDH1A1HSD11B1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118119600-A | SOS1 inhibitors and uses thereof | 治纳辅医药科技有限公司 | 2024-05-31 | — | — | CN | disclosed |