Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.33 |
| ▸ | CHRNG | P07510 | 1/20 | 0.33 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | CHRND | Q07001 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30949633 | 0.76 | KDM4E (0.39) | RAB9ANPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL30949636 | 0.76 | KDM4E (0.39) | RAB9ANPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL22207932 | 0.75 | GPR35 (0.34) | MEN1KMT2AALDH1A1SMN1; SMN2HTT | |
| SCHEMBL31697261 | 0.75 | GPR35 (0.34) | MEN1KMT2AALDH1A1SMN1; SMN2HTT | |
| SCHEMBL26987267 | 0.75 | CA12 (0.41) | KMT2AALDH1A1KDM4EGAAHPGD | |
| SCHEMBL6744852 | 0.73 | MEN1 (0.39) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL30949575 | 0.72 | MAPK1 (0.43) | MEN1KMT2AALDH1A1KDM4EGLA | |
| SCHEMBL30949542 | 0.70 | ALDH1A1 (0.40) | RAB9AMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL6745439 | 0.69 | TLR8 (0.45) | RAB9ANPC1MEN1KMT2AGAA | |
| SCHEMBL13377370 | 0.69 | MAOA (0.43) | RAB9ANPC1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4652154-A1 | NOVEL ALPK1 INHIBITORS | Pyrotech (Beijing) Biotechnology Co., Ltd. (CN) | 2025-11-26 | — | — | EP | disclosed |
| WO-2024153225-A1 | NOVEL ALPK1 INHIBITORS | PYROTECH (BEIJING) BIOTECHNOLOGY CO., LTD. (CN) | 2024-07-25 | — | — | WO | disclosed |