Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL1B | P01584 | 20/20 | 0.48 |
| ▸ | TNF | P01375 | 3/20 | 0.43 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30951380 | 0.85 | HTR7 (0.40) | IL1B | |
| SCHEMBL30951394 | 0.85 | HTR7 (0.40) | IL1B | |
| SCHEMBL22695045 | 0.71 | IL1B (0.61) | IL1BTNFNLRP3 | |
| SCHEMBL31637414 | 0.69 | IL1B (0.51) | IL1BTNFNLRP3 | |
| SCHEMBL30951378 | 0.69 | NLRP3 (0.43) | IL1BTNFNLRP3 | |
| SCHEMBL31637350 | 0.68 | IL1B (0.47) | IL1BTNFNLRP3 | |
| SCHEMBL22695042 | 0.68 | IL1B (0.57) | IL1BTNFNLRP3 | |
| SCHEMBL22655138 | 0.68 | IL1B (0.57) | IL1BTNFNLRP3 | |
| SCHEMBL22654856 | 0.67 | IL1B (0.58) | IL1BTNFNLRP3 | |
| SCHEMBL22670556 | 0.67 | IL1B (0.60) | IL1BTNFNLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024094150-A1 | NLRP3 INFLAMMASOME INHIBITORS AND USES THEREOF | INSILICO MEDICINE IP LIMITED (CN) | 2024-05-10 | — | — | WO | disclosed |