SCHEMBL30952002

SCHEMBL30952002

CN1C(=O)C(O)(c2ccc(S(N)(=O)=O)cc2)c2ccccc21

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RECQL P46063 1/20 0.46
RAB9A P51151 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
RAD52 P43351 1/20 0.46
HTT P42858 1/20 0.45
PTGS2 P35354 1/20 0.43
KDM4E B2RXH2 1/20 0.43
HCRTR1 O43613 1/20 0.43
LMNA P02545 1/20 0.43
MAPT P10636 1/20 0.43
CA1 P00915 2/20 0.42
CA2 P00918 2/20 0.42
CA12 O43570 1/20 0.42
CA9 Q16790 1/20 0.42
ALDH1A1 P00352 1/20 0.41
SCN9A Q15858 2/20 0.40
ADAMTS5 Q9UNA0 1/20 0.39
CA4 P22748 1/20 0.39
CA7 P43166 1/20 0.39
MEN1 O00255 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30951971 0.83 CNR1 (0.51) CA2CA12CA9ALDH1A1SCN9A
SCHEMBL31389174 0.82 RAB9A (0.58) RECQLRAB9ASMN1; SMN2RAD52HTT
SCHEMBL30951955 0.81 PTGS2 (0.43) RAD52PTGS2KDM4EHCRTR1LMNA
SCHEMBL30951994 0.79 SCN9A (0.39) HTTPTGS2CA1CA2CA12
SCHEMBL30951944 0.78 CA2 (0.43) CA1CA2CA12CA9CA4
SCHEMBL30952006 0.78 SCN9A (0.50) PTGS2KDM4EMAPTCA1CA2
SCHEMBL30951949 0.75 SCN9A (0.76) CA1CA2CA12CA9SCN9A
SCHEMBL30951988 0.75 SCN9A (0.60) CA1CA2CA12CA9SCN9A
SCHEMBL30951997 0.75 SCN9A (0.62) CA1CA2CA12CA9SCN9A
SCHEMBL30951993 0.75 SCN9A (0.62) CA1CA2CA12CA9SCN9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4630401-A2 CARBONIC ANHYDRASE ENZYME INHIBITORS AND METHODS OF USE THEREOF Rutgers, the State University of New Jersey (US) 2025-10-15 EP disclosed
WO-2024124023-A2 CARBONIC ANHYDRASE ENZYME INHIBITORS AND METHODS OF USE THEREOF RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2024-06-13 WO disclosed