Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.43 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | PIK3C2B | O00750 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.36 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24744761 | 1.00 | KDM4E (0.46) | KDM4EALDH1A1PKN1PKN2KMT2A | |
| SCHEMBL24744762 | 0.88 | PKN1 (0.47) | KDM4EALDH1A1PKN1PKN2KMT2A | |
| SCHEMBL29893726 | 0.88 | PKN1 (0.47) | KDM4EALDH1A1PKN1PKN2KMT2A | |
| SCHEMBL24774224 | 0.83 | ALDH1A1 (0.46) | KDM4EALDH1A1PKN1PKN2KMT2A | |
| SCHEMBL31090614 | 0.83 | DHODH (0.48) | KDM4EALDH1A1CACNA1BPIK3C2BPIK3CD | |
| SCHEMBL24745714 | 0.83 | DHODH (0.48) | KDM4EALDH1A1CACNA1BPIK3C2BPIK3CD | |
| SCHEMBL24744906 | 0.81 | KDM4E (0.37) | KDM4EALDH1A1CACNA1BPIK3C2BHTT | |
| SCHEMBL31090610 | 0.81 | PIK3C2B (0.40) | KDM4EALDH1A1CACNA1BPIK3C2BPIK3CD | |
| SCHEMBL24745592 | 0.81 | PIK3C2B (0.40) | KDM4EALDH1A1CACNA1BPIK3C2BPIK3CD | |
| SCHEMBL24745459 | 0.81 | ALDH1A1 (0.37) | KDM4EALDH1A1CACNA1BPIK3C2BLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4630415-A1 | TARGETED PROTEIN DEGRADATION USING PRODRUGS OF BIFUNCTIONAL COMPOUNDS THAT BIND UBIQUITIN LIGASE AND TARGET MCL-1 PROTEIN | Captor Therapeutics S.A. (PL) | 2025-10-15 | — | — | EP | disclosed |
| WO-2024121259-A1 | TARGETED PROTEIN DEGRADATION USING PRODRUGS OF BIFUNCTIONAL COMPOUNDS THAT BIND UBIQUITIN LIGASE AND TARGET MCL-1 PROTEIN | CAPTOR THERAPEUTICS S.A. (PL) | 2024-06-13 | — | — | WO | disclosed |