Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GSK3B | P49841 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.38 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.36 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.36 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24744761 | 0.83 | KDM4E (0.46) | ALDH1A1KDM4ETSHRKMT2AHPGD | |
| SCHEMBL30952847 | 0.83 | KDM4E (0.46) | ALDH1A1KDM4ETSHRKMT2AHPGD | |
| SCHEMBL24744762 | 0.81 | PKN1 (0.47) | ALDH1A1KDM4EGAASMN1; SMN2KMT2A | |
| SCHEMBL29893726 | 0.81 | PKN1 (0.47) | ALDH1A1KDM4EGAASMN1; SMN2KMT2A | |
| SCHEMBL20494743 | 0.80 | NR1H2 (0.45) | L3MBTL1 | |
| SCHEMBL30951936 | 0.78 | ALDH1A1 (0.64) | ALDH1A1KDM4EGSK3BGAASMN1; SMN2 | |
| SCHEMBL8597440 | 0.75 | KDM4E (0.40) | ALDH1A1KDM4ESMN1; SMN2TSHRKMT2A | |
| SCHEMBL24745490 | 0.74 | ALDH1A1 (0.40) | ALDH1A1KDM4EGAASMN1; SMN2TSHR | |
| SCHEMBL24744900 | 0.72 | ALDH1A1 (0.38) | ALDH1A1KDM4EGAASMN1; SMN2HSD17B10 | |
| SCHEMBL9982679 | 0.72 | L3MBTL1 (0.44) | ALDH1A1KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022255888-A1 | TARGETED PROTEIN DEGRADATION USING BIFUNCTIONAL COMPOUNDS THAT BIND UBIQUITIN LIGASE AND TARGET MCL-1 PROTEIN | CAPTOR THERAPEUTICS S.A. (PL) | 2022-12-08 | — | — | WO | disclosed |